ischemic heart disease - CAUSES


ischemic heart disease
CAUSES
By 1940 the production epidemiological ischemic heart disease is limited to interesting observations linking differences in the incidence of cardiovascular disease in different regions with different patterns also supply.

After the Second World War took place between several epidemiological studies highlighting the important role of the physiologist-epidemiologist Ankle Keys, United States, who worked hard in the diet-CHD relations. 

It then works in 2 directions:
on the one hand are performed studies to compare populations from different geographical regions to examine what's different in the people and conditions in these areas to explain different incidence rates presented in them, and develop other cohort studies where it is compared to individuals in order to measure differential risk by exposure to potential causative factors. One such study, which has provided a great deal of valuable information the Framingham Heart Study began in the States in 1948.
Based on the results were obtained in these studies were developed as many studies to establish the effect on the incidence achieved with various interventions, and further studies to find factors that explain this variation does not explained by risk factors "conventional", which continues until now (in fact, the term risk factor for common use were made after be coined by the Framingham study).

The first conclusions of the studies conducted in the mid-twentieth century brought to the arterial hypertension, hypercholesterolemia and smoking

as major risk factors for IHD;
also state that the simultaneous presence of Several of them has an effect not only additive, but multiplicative risk of each factor separately. Table 1 shows the results a study by the American Heart Association published in 1973 in which this effect is seen multiplicative.

In the first epidemiological studies to have now identified more than 300 risk factors for IHD. Table 2 shows some of the most important risk factors for coronary heart disease.

This entry was posted in . Bookmark the permalink.